Absorption of drugs

 ✅ Absorption of drugs 


👉Drug absorption refers to the process by which a drug enters the bloodstream from its site of administration, such as the digestive tract (oral), the skin (topical), or the bloodstream (intravenous). The key factors affecting drug absorption include:


👉Route of Administration: The method used to introduce the drug into the body, like oral (swallowing a pill), intravenous (directly into the bloodstream), or topical (applied to the skin).


👉Drug Formulation: The drug's physical form, such as a tablet, liquid, or injection, can affect how quickly and completely it is absorbed.


👉Blood Flow: The blood supply to the administration site can influence the rate of absorption. More blood flow generally means faster absorption.


👉Drug Properties: The drug's chemical properties, such as solubility and size, impact its ability to cross biological membranes and be absorbed.


👉Gastrointestinal Factors: In the case of oral drugs, factors in the stomach and intestines, like pH and presence of food, can affect absorption.


👉First-Pass Effect: For orally administered drugs, they may undergo metabolism in the liver before entering the systemic circulation, which can reduce their effectiveness.


👉Drug-Drug Interactions: Interactions with other drugs or substances can affect the absorption of a drug.


👉In summary, drug absorption is a complex process influenced by multiple factors that determine how and to what extent a drug enters the bloodstream, ultimately affecting its therapeutic effect.

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